Space Station Science: Biological Research

Living and Working Aboard Station

 Join us on Facebook Live for a conversation with astronaut Kate Rubins and the director of the National Institutes for Health on Tuesday, October 18 at 11:15 a.m. ET.

Astronaut Kate Rubins has conducted out of this world research aboard Earth’s only orbiting laboratory. During her time aboard the International Space Station, she became the first person to sequence DNA in space. On Tuesday, she’ll be live on Facebook with National Institute of Health director Francis Collins, who led the effort to map the human genome. You can submit questions for Kate using the hashtag #SpaceChat on Twitter, or during the live event. Here’s a primer on the science this PhD astronaut has been conducting to help inspire your questions: 

Kate has a background in genomics (a branch of molecular genetics that deals with the study of genomes,specifically the identification and sequencing of their constituent genes and the application of this knowledge in medicine, pharmacy,agriculture, and other fields). When she began her tenure on the station, zero base pairs of DNA had been sequenced in space. Within just a few weeks, she and the Biomolecule Sequencer team had sequenced their one billionth base of DNA aboard the orbital platform.

“I [have a] genomics background, [so] I get really excited about that kind of stuff,” Rubins said in a downlink shortly after reaching the one billion base pairs sequenced goal.

Learn more about this achievement:

+First DNA Sequencing in Space a Game Changer

+Science in Short: One Billion Base Pairs Sequenced

Why is DNA Sequencing in Space a Big Deal?

A space-based DNA sequencer could identify microbes, diagnose diseases and understand crew member health, and potentially help detect DNA-based life elsewhere in the solar system.

+Why Sequencing DNA in Space is a Big Deal

https://youtu.be/1N0qm8HcFRI 

Miss the Reddit AMA on the subject? Here’s a transcript:

+NASA AMA: We just sequenced DNA in space for the first time. Ask us anything! 

NASA and Its Partnerships

We’re not doing this alone. Just like the DNA sequencing was a collaborative project with industry, so is the Eli Lilly Hard to Wet Surfaces investigation, which is a partnership between CASIS and Eli Lilly Co. In this experiment aboard the station, astronauts will study how certain materials used in the pharmaceutical industry dissolve in water while in microgravity. Results from this investigation could help improve the design of tablets that dissolve in the body to deliver drugs, thereby improving drug design for medicines used in space and on Earth. Learn more about what we and our partners are doing:

+Eli Lilly Hard to Wet Surfaces – been happening the last week and a half or so

Researchers to Test How Solids Dissolve in Space to Design Better Tablets and Pills on Earth

With our colleagues at the Stanford University School of Medicine, we’re also investigating the effects of spaceflight on stem cell-derived heart cells, specifically how heart muscle tissue, contracts, grows and changes  in microgravity and how those changes vary between subjects. Understanding how heart muscle cells change in space improves efforts for studying disease, screening drugs and conducting cell replacement therapy for future space missions. Learn more:

+Heart Cells

+Weekly Recap From the Expedition Lead Scientist for Aug. 18, 2016 

It’s Not Just Medicine

Kate and her crew mates have also worked on the combustion experiments.

Kate has also worked on the Bigelow Expandable Activity Module (BEAM), an experimental expandable capsule that docks with the station. As we work on our Journey to Mars, future space habitats  are a necessity. BEAM, designed for Mars or other destinations, is a lightweight and relatively simple to construct solution. Kate has recently examined BEAM, currently attached to the station, to take measurements and install sensors.

Kate recently performed a harvest of the Plant RNA Regulation experiment, by removing seed cassettes and stowing them in cold stowage.

The Plant RNA Regulation investigation studies the first steps of gene expression involved in development of roots and shoots. Scientists expect to find new molecules that play a role in how plants adapt and respond to the microgravity environment of space, which provides new insight into growing plants for food and oxygen supplies on long-duration missions. Read more about the experiment:

+Plant RNA Harvest

NASA Astronaut Kate Rubins is participating in several investigations examining changes in her body as a result of living in space. Some of these changes are similar to issues experienced by our elderly on Earth; for example, bone loss (osteoporosis), cardiovascular deconditioning, immune dysfunction, and muscle atrophy. Understanding these changes and how to prevent them in astronauts off the Earth may help improve health for all of us on the Earth. In additional, the crew aboard station is also working on more generalized studies of aging.

+ Study of the effects of aging on C. elegans, a model organism for a range of biological studies.

RIP

While flying over Boston, Leonard Nimoy’s birthplace, NASA Astronaut Terry Virts pays tribute to the Star Trek star http://nbcnews.to/1AUElvf

6 Ways Earth Observations Tackle Real-World Problems

This summer, 30 research projects were launched by recent college graduates and early career professionals as part of our DEVELOP program. The aim is to use our satellite observations of Earth to address an environmental or public policy issue. And they have just 10 weeks to do it! On Aug. 10, 2016, the “DEVELOPers” gathered at our Headquarters in Washington, DC to showcase their results. So, how can Earth observations solve real-world problems? Let’s take a look:

1. They help land managers identify the locations of invasive species.

Austin Haney, DEVELOP project co-lead at University of Georgia, has seen first-hand how an invasive species can affect the ecosystem of Lake Thurmond, a large reservoir that straddles the border between Georgia and South Carolina. Birds in the area “behave visibly different,” he said, after they consume a toxic cyanobacteria that lives on Hydrilla verticillata, an invasive aquatic plant. Ingesting the toxin causes a neurodegenerative disease and ultimately death. Scores of birds have been found dead near lake areas where large amounts of the toxin-supporting Hydrilla grow. To help lake managers better address the situation, Haney and project members developed a tool that uses data from the Landsat 8 satellite to map the distribution of Hydrilla across the lake. 

Image Credit: NASA/Bill Ingalls

2. They help identify wildlife habitat threatened by wildfires.

Maps that depict habitat and fire risk in eastern Idaho previously stopped short of Craters of the Moon National Monument and Preserve, where shrubs and grasses transition to a sea of ankle-twisting basalt. But the environment is not as inhospitable as it first appears. Throughout the monument there are more than 500 kipukas —pockets of older lava capable of supporting some vegetation. That means it is also prone to burning. Project lead Courtney Ohr explained how her team used data from the Landsat 8 and Sentinel-2 satellites to develop a model that can simulate the area’s susceptibility to wildfires. Decision makers can use this model to monitor the remote wildlife habitat from afar.

Image Credit: NASA/Bill Ingalls

3. In conjunction with Instagram, they help find seaweed blooms

Who knew that Instagram could be a tool for science? One DEVELOP team searched for photographs of massive seaweed (sargassum) blooms in the Caribbean, mapped the locations, and then checked what satellites could see. In the process, they tested two techniques for finding algae and floating vegetation in the ocean.

Image Credit: Caribbean Oceans Team

4. They help conserve water by reducing urban stormwater runoff.

Atlanta’s sewer system is among the nation’s most expensive. Yet, the city still struggles with stormwater. It’s an uphill climb as new construction paves over more of the city, hindering its ability to absorb rain. The University of Georgia DEVELOP team partnered with The Nature Conservancy to address the problem.

Using satellite imagery, the team was able to pinpoint areas well-poised to capture more of the city’s runoff. They identified 17 communities ripe for expanding green infrastructure and reforestation. The team used the Land-Use Conflict Identification Strategy and Soil and Water Assessment Tool models and Landsat and Terra satellite data. Their analysis provides local groups with a working picture of the city’s water resources.

Image Credit: NASA/Bill Ingalls

5. They show the spread of the mite eating away Puerto Rico’s palm trees.

The red palm mite has devastated Puerto Rico’s trees in recent years. The insect chewed its way through coconut palms, bananas, and plantains on the island in the recent decade. Its spread has hurt crops across the Caribbean.

A DEVELOP team led by Sara Lubkin analyzed satellite imagery to track the mites’ rapid spread from 2002. The team mapped changes to vegetation, such as yellowing, and differences in canopy structure. They made use of imagery from Landsat, Hyperion, IKONOS, and aerial views. Their work can be used to mitigate current mite infestations and monitor and prevent future ones.

Image Credit: NASA/Bill Ingalls

6. They evaluate landslide-prone areas in the developing world

One team of DEVELOPers took on several projects to aid people in developing nations. This team from Alabama examined satellite imagery to find past landslides in the African nation of Malawi. Factors such as flooding after long periods of drought have made the country increasingly prone to landslides. Blending maps of the landscape, rainfall data, and population centers, the young researchers assessed the areas most at risk—and most in need of education and support—from landslides.

Image Credit: East Africa Disasters II Team

Want to read more about DEVELOP projects, or get involved? Summaries, images, and maps of current and past projects can be viewed HERE. You can also learn how to apply for the DEVELOP program HERE.  

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Explanation: Big, beautiful spiral galaxy NGC 7331 is often touted as an analog to our ownMilky Way. About 50 million light-years distant in the northern constellation Pegasus, NGC 7331 was recognized early on as a spiral nebulaand is actually one of the brighter galaxies notincluded in Charles Messier''s famous 18th century catalog. Since the galaxy''s disk is inclined to our line-of-sight, long telescopic exposures often result in an image that evokes a strong sense of depth. The effect is further enhanced in this sharp image from a small telescope by galaxies that lie beyond the gorgeous island universe. The most prominent background galaxies are about one tenth theapparent size of NGC 7331 and so lie roughly ten times farther away. Their close alignment on the sky with NGC 7331 occurs just by chance. Seen through faint foreground dust clouds lingering above the plane of Milky Way, this visual grouping of galaxies is known as theDeer Lick Group.

'NASA's Hubble Telescope Detects ‘Sunscreen' Layer on Distant Planet': via #NASA_APP

Profile of a World War 2 Test Pilot

Is Proxima b another Earth? It’s difficult to answer because no one has actually “seen” this distant planet which orbits the red dwarf star Proxima Centauri right in theGoldilocks Zone. Scientists have merely concluded that Proxima b (which is about 4.2 light years away from Earth) is right where it should be, by observing the regular, subtle changes in Proxima Centauri’s color. Proxima b is tidally locked to its star — which means one side of it is always facing Proxima Centauri, and the other side is perpetually dark. With just an 11.2-year revolution, it lies very close to its star, although red-dwarf stars are not as hot as yellow-dwarves (like our Sun).  There is a possibility that water exists on Proxima b, and that it has an atmosphere protecting it from extreme heat, and scattering heat even to its dark side.  How can we be sure? Harvard’s Avi Loeb and astronomer Laura Kreidberg propose that we use NASA’s James Webb Space Telescope (JWST). UNCERTAINTIES The long-delayed JWST is set to launch by 2018 (originally 2011). Loeb explains that if a rocky planet, like Proxima b, has an atmosphere, it would absorb light from its star and re-emit it as infrared light. Incidentally, the JWST is specifically designed to observe infrared light. The JWST can take photos of infrared light on the surface Proxima b, looking for patterns that would confirm whether or not this exoplanet has water or is covered by an atmosphere. Things aren’t so simple, however. The proposed method may be doable. But there are other factors that have to be considered. For instance, the existence of an atmosphere may not guarantee life, says astrophysicist Ed Turner of Princeton University. Proxima b may be like Venus, with an atmosphere 90 times thicker than ours, and extreme heat. Still, Loeb’s and Kriedberg’s plan is the only option we have for a glimmer of an answer about this “Earth next-door”. References: Business Insider, Scientific American

We have been expecting you Mr Handle......

When magnetic ferrofluid comes in contact with a magnetic object, it becomes a moving sculpture that reflects the shape of the object’s magnetic field. Source